The RVC Biofund's portfolio company National bioservice has launched a service to produce tissue macrochips (TMA), designed to study cross- reactivity of antibodies to human tissues. These studies are a necessary step in developing therapeutic and diagnostic monoclonal antibodies and marketing domestic biosimilars.
The tissue macrochips designed by National BioService will become the first product in Russia and worldwide to correspond simultaneously to all major foreign and domestic regulatory requirements imposed on the way the cross-reactivity of antibodies should be tested.
Until now no company in the world ever produced tissue macrochips which would comply with the standards imposed by all the chief regulators(FDA, EMA, Health Ministry of the Russian Federation ) . Under this circumstance the manufacturers were forced to duplicate the studies required to register medical products in different countries. Russia does not produce similar products and the use of foreign counterparts is hindered by logistics and customs barriers on the one hand and their high cost on the other hand. Besides, the characteristics of TMA do not always comply with the requirements of Health Ministry of the Russian Federation.
The macrochip is a thin glass plate, on which up to 38 human tissues can be positioned. Besides, the TMA will have a unique design in terms of tissue composition. Since the production of TMA is compliant with these parameters, the product is universally applicable in situations when studies on cross-reactivity of antibodies are conducted by biopharmaceutical companies and contract research centers both in Russia and abroad.
When the research into cross — reactive antibodies is effected by home-made macrochips, its cost will be reduced two fold, the customs barriers will disappear so eventually the process of developing medical products will become less money-consuming and more energetic.
The TMA technological service launched by National BioService will be used further to increase the range of tissue macrochips: focal TMA for cancer and other pathological tissues, TMA for various species used in the preclinical studies of antibodies.
About National BioService LLC
NBS (National BioService) is the first research biobank and bioservice in Russia that operates in compliance with the requirements of the International Society for Biological and Environmental Repositories NBS was established to be instrumental in developing the infrastructure of biomedical research in Russia and integrating into international activities, aimed at improving human healthcare and developing personalized medicine .
About RVC Biofund
In June 2010, the Board of Directors of RVC approved the concept of RVC Biofund. The fund began its operations in the beginning of 2011. In its investments RVC's Biofund focuses on innovative biopharmaceutical companies and service companies providing contract laboratory, analytical and consulting services to biotechnology, pharmaceutical and medical companies.
For further information, please contact:
OJSC «RVC» Public Relation Department
tel: (495) 777-0104,